Pharmacology – Antimicrobials – Protein Synthesis Inhibitors (Tetracyclines, Glycycyclines, Aminoglycosides, Macrolides, Oxazolidinones, Streptogramins, Lincosamide, Chloramphenicol, Rifaximin, Mupirocin)

1. Concept of Protein Synthesis

2. Classification of Protein Synthesis Inhibitors based on

a. their site of action

b. Spectrum of activity

3. Tetracyclines

a. Drugs name

b. Mechanism of action

c. Route of administration

d. Use

e. Mechanism of Resistance

f. Pharmacokinetics

g. Adverse Effects

h. Advice

I. Contraindications

4. Glycycyclines

5. Aminoglycosides

a. Drugs name

b. Mechanism of action

c. Route of administration

d. Use

e. Mechanism of Resistance

f. Pharmacokinetic

g. Adverse Reactions

h. Advice

I. Contraindications

6. Macrolides

a. Drugs name

b. Mechanism of action

c. Route of administration.

d. Use

e. Mechanism of Resistance

f. Pharmacokinetics

g. Adverse Effects

h. AdviceI

i.. Contraindications

j. Drug interactions

7. Oxazolidinones

8. Streptogramins

9. Lincosamide

10. Chloramphenicol

11. Rifaximin

12. Mupirocin